Half of patients hospitalised have at least one symptom two years on

Two years later, half of the group of patients admitted to COVID-19 in Wuhan, China, Lancet Respiratory Medicine.. This study followed 1192 participants in Wuhan who were infected with SARS-CoV-2 during the first phase of the 2020 pandemic.

Although physical and mental health generally improved over time, this study found that COVID-19 patients still tended to have lower health and quality of life than the general population. This is especially true for participants with long COVIDs. Participants usually have at least one symptom, such as fatigue, shortness of breath, and sleep problems, two years after their first illness.1

The long-term health effects of COVID-19 remain largely unknown, as the longest follow-up to date lasts about a year.2 The lack of a baseline of pre-COVID-19 health and comparison with the general population in most studies also made it difficult to determine how well patients with COVID-19 recovered.

Professor Bin Cao, the lead author of the Japan-China Friendship Hospital in China, said: Full recovery from COVID-19. Continued follow-up of COVID-19 survivors, especially those with long-term COVID symptoms, is essential to understanding the longer course of the disease, as well as further investigation of the benefits of rehabilitation programs for recovery. is. Need to provide ongoing support to a significant proportion of people who have been infected with COVID-19 and understand how vaccines, new therapies, and variants affect long-term health outcomes. It is clear that there is. “3

The authors of the new study sought to analyze the long-term health outcomes of hospitalized COVID-19 survivors and the specific health effects of long-term COVID. They were 1192 people with acute COVID-19 treated at Jin Gin Yan Hospital in Wuhan, China during the 6 months, 12 months and 2 years from January 7th to May 29th, 2020. We evaluated the health status of the participants.

The assessment included a 6-minute walk test, laboratory tests, symptoms, mental health, health-related quality of life (if returning to work after discharge), and a questionnaire regarding the use of healthcare. The adverse effects of long COVID on quality of life, athletic performance, mental health and health care use were determined by comparing participants with and without long COVID symptoms. The 2-year health outcome was determined using controls with matching age, gender, and comorbidity in the general population with no history of COVID-19 infection.

Two years after the first illness, patients with COVID-19 are in poorer health than the general population, with 31% reporting fatigue or weakness and 31% reporting sleep disorders. The proportion of non-COVID-19 participants who reported these symptoms was 5% and 14%, respectively.

Patients with COVID-19 were also more likely to report many other symptoms, including joint pain, palpitation, dizziness, and headache. In quality of life questionnaires, COVID-19 patients report pain and discomfort (23%) and anxiety and depression (12%) more than non-COVID-19 participants (5% and 5%, respectively). There were many things.

About half of the study participants reported that they had long COVID symptoms at 2 years and had a lower quality of life than those without long COVID. In the mental health questionnaire, 35% reported pain or discomfort and 19% reported anxiety or depression. The proportion of COVID-19 patients without long COVID who reported these symptoms was 10% and 4%, respectively, over 2 years. Long COVID participants were more likely to report mobility (5%) or activity level (4%) problems than participants without long COVID (1% and 2%, respectively).

The authors acknowledged the limitations of the study, including moderate response rates. The percentage of participants who received oxygen increased slightly. It was a single-center study from the early days of the pandemic.


1.-National Institute for Health and Care Technology-Scotland Inter-University Guidelines Network-Royal College of General Practicism. COVID-19 Rapid Guidelines: Managing the long-term effects of COVID-19. https://www.nice.org.uk/guidance/ng188
2.-Soriano-JB Mercy-S Marshall-JC Relan-P Diaz JV-COVID-19 On behalf of the WHO Clinical Case Definition Working Group on Post-Status. Clinical case definition of post-COVID-19 status by Delphi consensus. Lancet Infect Dis. 2021; 22: e102-e107
3.-Huang L-Yao Q-GuX-etc. 1-year outcome in hospital survivors of COVID-19: Longitudinal cohort study. Lancet. 2021; 398: 747-758

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